Two new sesquiterpenoids from the marine-sediment-derived fungus Trichoderma harzianum P1-4

被引:17
|
作者
Fang, Sheng-Tao [1 ]
Wang, Ying-Jie [1 ]
Ma, Xin-Yue [1 ]
Yin, Xiu-Li [1 ]
Ji, Nai-Yun [1 ]
机构
[1] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China
基金
中国国家自然科学基金;
关键词
Trichoderma harzianum; sesquiterpenoid; marine fungus; cyclonerodiol; ENDOPHYTIC FUNGUS; SECONDARY METABOLITES; CYCLONERODIOL; DERIVATIVES; STRAINS; ACID;
D O I
10.1080/14786419.2018.1522314
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Three cyclonerane sesquiterpenoids, including the known cyclonerodiol (1), together with its new derivatives, (10E)-12-acetoxy-10-cycloneren-3,7 -diol (2) and 12-acetoxycycloneran-3,7-diol (3) were isolated from the cultures of marine-sediment-derived fungus Trichoderma harzianum P1-4. The structures of the new compounds (2 and 3) were elucidated based on extensive spectroscopic methods (1D/2D NMR and HR-MS) and optical rotation analysis.
引用
收藏
页码:3127 / 3133
页数:7
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