An update on the role of long non-coding RNAs in psoriasis

被引：16

作者：

Song, Jian-Kun ^{[1
,2
]}

Yin, Shuang-Yi ^{[3
]}

Li, Wei ^{[3
]}

Li, Xiao-Dong ^{[4
,5
]}

Luo, Yue ^{[1
]}

Luo, Ying ^{[2
]}

Xing, Meng ^{[1
]}

Li, Bin ^{[1
,2
,6
]}

Kuai, Le ^{[1
,2
]}

机构：

[1] Shanghai Univ Tradit Chinese Med, Yueyang Hosp Integrated Tradit Chinese & Western, Dept Dermatol, Shanghai 200437, Peoples R China

[2] Shanghai Acad Tradit Chinese Med, Inst Dermatol, Shanghai 201203, Peoples R China

[3] Henan Univ, Huaihe Hosp, Kaifeng 475001, Henan, Peoples R China

[4] Henan Univ, Dept Urol Surg, Huaihe Hosp, Kaifeng 475001, Henan, Peoples R China

[5] Henan Univ, Inst Evidence Based Med & Knowledge Translat, Kaifeng 475001, Henan, Peoples R China

[6] Shaanxi Tradit Chinese Med Hosp, Dept Dermatol, Xian 710004, Shaanxi, Peoples R China

来源：

CHINESE MEDICAL JOURNAL | 2021年 / 134卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Long non-coding RNAs (LncRNA); Psoriasis; Keratinocytes; T cells; Dendritic cells;

D O I：

10.1097/CM9.0000000000001243

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational levels; however, the specific regulatory mechanisms of lncRNAs in psoriasis remain largely unexplored. This review provides an overview of recent studies investigating mechanisms and functions of lncRNAs in psoriasis, especially focusing on the role of lncRNAs in keratinocytes, T cells, and dendritic cells.

引用

页码：379 / 389

页数：11

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Yin Shuang-Yi
Li Wei
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Li Bin
Kuai Le
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