Management of patients with HBeAg-negative chronic hepatitis B

被引：15
|
作者：
Saikia, Nripen [1 ]
Talukdar, Rupjyoti [1 ]
Mazumder, Subhasish [1 ]
Khanna, Sudeep [1 ]
Tandon, Rakesh [1 ]
机构：
[1] Pushpawati Singhania Res Inst, Dept Gastroenterol, New Delhi 110017, India
来源：
POSTGRADUATE MEDICAL JOURNAL | 2007年 / 83卷 / 975期
关键词：
D O I：
10.1136/pgmj.2006.044826
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Chronic hepatitis B (CHB) is one of the leading causes of morbidity and mortality worldwide. Although various drugs are available for the treatment of CHB, emergence of the hepatitis B e antigen ( HBeAg)-negative mutant variant, specifically in Asia, the Middle East and southern Europe, is creating a new challenge as this variant is less responsive to available treatments. HBeAg-negative CHB rapidly progresses to cirrhosis and its related complications. This review discusses the available literature on the approved and under-trial treatment options and their respective efficacies for HBeAg-negative CHB.
引用
收藏
页码：32 / 39
页数：8
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