Invasive pulmonary aspergillosis after treatment with tocilizumab in a patient with COVID-19 ARDS: a case report

被引:18
|
作者
Witting, Celeste [1 ]
Quaggin-Smith, Jessica [2 ]
Mylvaganam, Ruben [3 ]
Peigh, Graham [2 ]
Angarone, Michael [4 ]
Flaherty, James D. [5 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
[2] Northwestern Univ, Dept Internal Med, McGaw Med Ctr, Chicago, IL 60611 USA
[3] Northwestern Univ, Dept Internal Med, McGaw Med Ctr, Div Pulm & Crit Care Med, Chicago, IL 60611 USA
[4] Northwestern Mem Hosp, Div Infect Dis, Dept Internal Med, Chicago, IL 60611 USA
[5] Northwestern Mem Hosp, Dept Internal Med, Div Cardiol, Chicago, IL 60611 USA
关键词
COVID-19; opportunistic Infections; fungal infections; aspergillosis; tocilizumab; pulmonary disease; INFECTIONS; RISK;
D O I
10.1016/j.diagmicrobio.2020.115272
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Tocilizumab, an interleukin-6 receptor antagonist, has been used to treat critically ill patients with coronavirus disease-2019. We present the case of a previously immunocompetent man with coronavirus disease 2019 who developed invasive pulmonary aspergillosis after treatment with tocilizumab, illustrating the importance of considering opportunistic infections when providing immune modulating therapy. (c) 2020 Elsevier Inc. All rights reserved.
引用
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页数:3
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