A facile and regioselective synthesis of 2,5-disubstituted pyrroles via gold-catalyzed cycloisomerization of acetylenylaziridines

被引：41
|
作者：
Chen, Dong-Dong [1 ]
Hou, Xue-Long [1 ]
Dai, Li-Xin [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 50期
基金：
中国国家自然科学基金;
关键词：
HIGHLY STEREOSELECTIVE-SYNTHESIS; 2-PROPYNYL-1,3-DICARBONYL COMPOUNDS; AMINATION/ANNULATION REACTIONS; EPOXY ALKYNES; AZIRIDINES; REARRANGEMENT; NUCLEOPHILES; EPOXIDES; ALCOHOLS; FURANS;
D O I：
10.1016/j.tetlet.2009.05.091
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Gold-catalyzed cycloisomerization reaction of acetylenylaziridines provides 2,5-disubstituted pyrroles in high yields. The presence of protic species accelerates the reaction rate and improves the yields of pyrrole products. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：6944 / 6946
页数：3
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