A nano-based thermotherapy for cancer stem cell-targeted therapy

被引:21
|
作者
Suo, Xiaomin [1 ,2 ]
Zhang, Juncai [1 ,2 ]
Zhang, Yue [1 ,2 ]
Liang, Xing-Jie [3 ]
Zhang, Jinchao [1 ,2 ]
Liu, Dandan [1 ,2 ]
机构
[1] Hebei Univ, Minist Educ, Key Lab Med Chem & Mol Diag, Baoding 071002, Peoples R China
[2] Hebei Univ, Coll Chem & Environm Sci, Chem Biol Key Lab Hebei Prov, Baoding 071002, Peoples R China
[3] Natl Ctr Nanoscience & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
关键词
NEGATIVE BREAST-CANCER; PHOTOTHERMAL THERAPY; HYALURONIC-ACID; CARBON NANOTUBES; MAGNETIC NANOPARTICLES; THERANOSTIC AGENT; GRAPHENE OXIDE; GOLD NANORODS; PROSPECTIVE IDENTIFICATION; MULTIDRUG-RESISTANCE;
D O I
10.1039/d0tb00311e
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Cancer stem cells (CSCs) exhibit high resistance to conventional therapy and are responsible for cancer metastasis and tumor relapse. Therefore, it is of significance to develop effective novel strategies to target CSCs for cancer therapies. The challenges associated with developing novel strategies include specific CSC targeting and overcoming their therapeutic resistance. In the present review, we summarize the various strategies for CSC-targeted cancer thermotherapy and combinational therapy, and the potential challenges and prospects for future work in this emerging field.
引用
收藏
页码:3985 / 4001
页数:17
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