Aspects of nitric oxide chemistry and biochemistry

With focus on the development and application of o-quinodimethanes as trapping agents for nitric oxide (Nitric Oxide Cheletropic Traps, NOCTs; Fluorescent Nitric Oxide Cheletropic Traps, FNOCTs) in vitro and in vivo, several aspects of the chemistry and biochemistry of nitric oxide are reported, including NO trapping from cell cultures and NO-releasing compounds, photochemical NO formation from nitrate solutions, interaction of NO with organic compounds, reaction of NO with nitroxide radicals, and the influence of oxygen on the cytotoxicity of NO-releasing compounds.