Location Matters: Synaptotagmin Helps Place Vesicles Near Calcium Channels

被引：3
|
作者：
McNeil, Benjamin D. [1 ]
Wu, Ling-Gang [1 ]
机构：
[1] NINDS, Bethesda, MD 20892 USA
来源：
NEURON | 2009年 / 63卷 / 04期
关键词：
CENTRAL SYNAPSE; NEUROTRANSMITTER RELEASE; TRANSMITTER RELEASE; CA2+; CALYX; DEPENDENCE;
D O I：
10.1016/j.neuron.2009.08.001
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Positioning releasable vesicles near voltage-gated calcium channels may ensure transmitter release upon calcium influx. Disruption of vesicle positioning may underlie short-term synaptic depression. However, how this positioning is achieved is unclear. In this issue of Neuron, Young and Neher find that synaptotagmin 2 helps to align readily releasable vesicles near calcium channels at nerve terminals.
引用
收藏
页码：419 / 421
页数：3
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