Chitosan-Based Porous Composites for Bone Tissue Engineering

被引：0

作者：

Sharikova, N. A. ^{[1
]}

Antipova, K. G. ^{[1
]}

Lukanina, K. I. ^{[1
]}

Stolyarova, D. Y. ^{[1
]}

Vdovichenko, A. Y. ^{[1
]}

Malakhov, S. N. ^{[1
]}

Krasheninnikov, S. V. ^{[1
]}

Kulikova, O. R. ^{[2
]}

Khramtsova, E. A. ^{[2
]}

Chvalun, S. N. ^{[1
]}

Grigoriev, T. E. ^{[1
]}

机构：

[1] Natl Res Ctr, Kurchatov Inst, Akad Kurchatova Pl, Moscow 123182, Russia

[2] Russian Acad Sci, Emanuel Inst Biochem Phys, Kosygina St 4, Moscow 119334, Russia

来源：

MACROMOLECULAR SYMPOSIA | 2022年 / 404卷 / 01期

关键词：

chitosan; composite materials; tissue engineering;

D O I：

10.1002/masy.202100398

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

This paper highlights the idea of creating highly porous composite materials for osteogenesis purposes based on chitosan with various functional fillers: reduced graphene oxide (rGO) and tricalcium phosphate (TCP). RGO filler is a carbon based electrical conductor with a high aspect ratio, therefore it is preferred for growth of osteoblasts populations with concomitant electrical stimulation. TCP is the main building block of bone tissue; hence composites filled with it can be used to accelerate the process of osteosynthesis. This paper considers the aspects of the functional agents influence on the morphological, electrically conductive, and mechanical characteristics of composites based on chitosan.

引用

页数：4

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