The brain-immune cells axis controls tissue specific immunopathology

被引:5
|
作者
Heyner, Maxi [1 ]
Schreier, Sarah [1 ]
Kroeger, Andrea [1 ,2 ]
机构
[1] Otto von Guericke Univ, Inst Med Microbiol & Hosp Hyg, Magdeburg, Germany
[2] Helmholtz Ctr Infect Res, Innate Immun & Infect Grp, Braunschweig, Germany
关键词
RESISTANCE; EXPRESSION;
D O I
10.1038/s41423-018-0176-y
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
During viral infections, cell death can be induced as a direct result of cytopathic virus replication in various cell types and tissues or as an immune response of the host to the infectious agent. This leads to an infiltration of inflammatory cells, causing subsequent tissue damage. The balance between effective elimination of the pathogen and prevention of fatal tissue damage is decisive for life. The host has developed various mechanisms to inhibit excessive immune responses.
引用
收藏
页码:101 / 103
页数:3
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