Whole-Genome Sequences of Two Borrelia afzelii and Two Borrelia garinii Lyme Disease Agent Isolates

被引:50
|
作者
Casjens, Sherwood R. [1 ]
Mongodin, Emmanuel F. [2 ]
Qiu, Wei-Gang [3 ]
Dunn, John J. [4 ]
Luft, Benjamin J. [5 ]
Fraser-Liggett, Claire M. [2 ]
Schutzer, Steve E. [6 ]
机构
[1] Univ Utah, Dept Pathol, Sch Med, Div Microbiol & Immunol, Salt Lake City, UT 84112 USA
[2] Univ Maryland, Sch Med, Inst Genome Sci, Dept Microbiol & Immunol, Baltimore, MD 21201 USA
[3] CUNY Hunter Coll, Dept Biol Sci, New York, NY 10065 USA
[4] Brookhaven Natl Lab, Dept Biol, Upton, NY 11793 USA
[5] SUNY Stony Brook, Dept Med, Hlth Sci Ctr, Stony Brook, NY 11794 USA
[6] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Med, Newark, NJ 07103 USA
基金
美国国家卫生研究院;
关键词
BURGDORFERI; SPIROCHETE;
D O I
10.1128/JB.05951-11
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Human Lyme disease is commonly caused by several species of spirochetes in the Borrelia genus. In Eurasia these species are largely Borrelia afzelii, B. garinii, B. burgdorferi, and B. bavariensis sp. nov. Whole-genome sequencing is an excellent tool for investigating and understanding the influence of bacterial diversity on the pathogenesis and etiology of Lyme disease. We report here the whole-genome sequences of four isolates from two of the Borrelia species that cause human Lyme disease, B. afzelii isolates ACA-1 and PKo and B. garinii isolates PBr and Far04.
引用
收藏
页码:6995 / 6996
页数:2
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