Using 100% oxygen does not alter the cardiovascular autonomic regulation during non-invasively simulated haemorrhage in healthy volunteers

被引：6

作者：

Kim, Y. K. ^{[1
]}

Jun, I. G. ^{[1
]}

Kim, S. R. ^{[2
]}

Hwang, J. H. ^{[1
]}

Cho, S. K. ^{[1
]}

Han, S. M. ^{[1
]}

Hwang, G. S. ^{[1
]}

机构：

[1] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Anaesthesiol & Pain Med, Seoul 138736, South Korea

[2] Kyung Hee Univ, Coll Med, Dept Obstet & Gynaecol, Seoul, South Korea

来源：

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2008年 / 36卷 / 02期

关键词：

acute haemorrhage; healthy subjects; oxygen; lower body negative pressure; heart rate variability; baroreflex sensitivity;

D O I：

10.1177/147323000803600203

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We tested the effect of 100% oxygen on heart rate (HR), arterial blood pressure (ABP), cardiac output (CO), stroke volume (SV), total peripheral resistance (TPR), HR variability (HRV), systolic blood pressure variability (SBPV) and baroreflex sensitivity (BRS) in 20 healthy volunteers during simulated haemorrhage induced by -40 mmHg lower body negative pressure (LBNP). HRV in the high frequency region (HRV,,), BRS, ABP and TPR were significantly increased, SBPV in the low frequency region (SBPV,,), CO and SV were unchanged, and HR was significantly decreased by 100% oxygen administration during normovolaemia. HRVHF, BRS, CO and SV were significantly decreased, SBPVLF and ABP were unchanged, and HR and TPR were significantly increased by LBNP during 21% or 100% oxygen administration. There were no significant differences in cardiovascular autonomic and haemodynamic responses to LBNP during 21% or 100% oxygen administration, suggesting that 100% oxygen does not alter normal cardiovascular autonomic responses during simulated hoemorrhage.

引用

页码：227 / 236

页数：10