Improving CAR T Cell Function by Reversing the Immunosuppressive Tumor Environment of Breast Cancer

被引：0
|
作者：
Bajgain, Pradip [1 ]
Tawinwung, Supannikar [1 ]
Watanabe, Norihiro [1 ]
Sukumaran, Sujita [1 ]
Ansari, Salma [1 ]
Anurathapan, Usanarat [1 ]
Heslop, Helen E. [1 ]
Rooney, Cliona M. [1 ]
Brenner, Malcolm K. [1 ]
Leen, Ann M. [1 ]
Vera, Juan F. [1 ]
机构：
[1] Baylor Coll Med, Ctr Cell & Gene Therapy, Houston, TX 77030 USA
来源：
MOLECULAR THERAPY | 2017年 / 25卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
283
引用
收藏
页码：134 / 134
页数：1
相关论文
共 50 条
  • [1] Improving CAR T cell function by reversing the immunosuppressive tumor environment of breast cancer
    Bajgain, Pradip
    Tawinwung, Supannikar
    Watanabe, Norihiro
    Sukumaran, Sujita
    Anurathapan, Usanarat
    Heslop, Helen E.
    Rooney, Cliona M.
    Brenner, Malcolm
    Leen, Ann M.
    Vera, Juan F.
    [J]. CANCER RESEARCH, 2018, 78 (04)
  • [2] Improving CAR T Cell Function by Reversing the Immunosuppressive Tumor Environment of Pancreatic Cancer
    Sukumaran, Sujita
    Mohammed, Somala
    Watanabe, Norihiro
    Bajgain, Pradip
    Ansari, Salma
    Anurathapan, Usanarat
    Heslop, Helen E.
    Rooney, Cliona R.
    Brenner, Malcolm K.
    Leen, Ann M.
    Vera, Juan F.
    [J]. MOLECULAR THERAPY, 2016, 24 : S297 - S297
  • [3] Improving CAR T cell function by reversing the immunosuppressive tumor environment of pancreatic cancer
    Mohammed, Somala
    Sukumaran, Sujita
    Anurathapan, Usanarat
    Bajgain, Pradip
    Heslop, Helen E.
    Rooney, Cliona M.
    Brenner, Malcolm K.
    Leen, Ann M.
    Vera, Juan F.
    [J]. CANCER RESEARCH, 2015, 75
  • [4] Improving CAR T cell function by reversing the immunosuppressive tumor microenvironment of pancreatic cancer
    Mohammed, Somala
    Sukumaran, Sujita
    Bajgain, Pradip
    Anurathapan, Usanarat
    Heslop, Helen E.
    Rooney, Cliona M.
    Brenner, Malcolm K.
    Leen, Ann M.
    Vera, Juan F.
    [J]. CANCER RESEARCH, 2015, 75
  • [5] Improving Chimeric Antigen Receptor-Modified T Cell Function by Reversing the Immunosuppressive Tumor Microenvironment of Pancreatic Cancer
    Mohammed, Somala
    Sukurnaran, Sujita
    Bajgain, Pradip
    Watanabe, Norihiro
    Heslop, Helen E.
    Rooney, Cliona M.
    Brenner, Malcolm K.
    Fisher, William E.
    Leen, Ann M.
    Vera, Juan F.
    [J]. MOLECULAR THERAPY, 2017, 25 (01) : 249 - 258
  • [6] N glycosylation inhibition hinders immunosuppressive tumor microenvironment cells improving CAR T cell efficacy
    Sirini, Camilla
    Greco, Beatrice
    Balestrieri, Chiara
    Camisa, Barbara
    Falcone, Laura
    El Khoury, Rita
    Botrugno, Oronzina
    Giovannoni, Giulio
    Tonon, Giovanni
    Brunetto, Emanuela
    Cangi, Maria Giulia
    Pedica, Federica
    Bergamini, Alice
    Ciceri, Fabio
    Bonini, Chiara
    Casucci, Monica
    [J]. CANCER RESEARCH, 2024, 84 (06)
  • [7] LIGHT/TNFSF14 promotes CAR-T cell trafficking and cytotoxicity through reversing immunosuppressive tumor microenvironment
    Zhang, Na
    Liu, Xiaohong
    Qin, Juliang
    Sun, Yue
    Xiong, Hao
    Lin, Boxu
    Liu, Kexin
    Tan, Binghe
    Zhang, Chenglin
    Huang, Chenshen
    Ren, Shancheng
    Liu, Mingyao
    Du, Bing
    [J]. MOLECULAR THERAPY, 2022, 31 (09) : 2575 - 2590
  • [8] CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation
    Bajgain, Pradip
    Tawinwung, Supannikar
    D'Elia, Lindsey
    Sukumaran, Sujita
    Watanabe, Norihiro
    Hoyos, Valentina
    Lulla, Premal
    Brenner, Malcolm K.
    Leen, Ann M.
    Vera, Juan F.
    [J]. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2018, 6
  • [9] Licensing of CAR-T cell persistence and function by STING agonist in breast cancer
    Xu, Nuo
    Serody, Jonathan
    Restifo, Nicholas
    Palmer, Douglas
    [J]. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
  • [10] Recognizing and reversing the immunosuppressive tumor microenvironment of head and neck cancer
    Tong, Charles C. L.
    Kao, Johnny
    Sikora, Andrew G.
    [J]. IMMUNOLOGIC RESEARCH, 2012, 54 (1-3) : 266 - 274
12345