The prevention of osteoporosis and sarcopenia in older adults

被引：53

作者：

Coll, Patrick P. ^{[1
,2
]}

Phu, Steven ^{[3
,4
]}

Hajjar, Samah H. ^{[2
,5
]}

Kirk, Ben ^{[3
,6
,7
]}

Duque, Gustavo ^{[3
,6
,7
]}

Taxel, Pam ^{[8
]}

机构：

[1] UConn Hlth, Dept Family Med, Farmington, CT 06030 USA

[2] UConn Hlth, Ctr Aging, 263 Farmington, Farmington, CT 06030 USA

[3] Univ Melbourne, Melbourne Med Sch, Dept Med Western Hlth, St Albans, Vic, Australia

[4] Neurosci Res Australia NeuRA, Falls Balance & Injury Res Ctr, Sydney, NSW, Australia

[5] Taibah Univ, Dept Med, Madina, Saudi Arabia

[6] Univ Melbourne, Australian Inst Musculoskeletal Sci AIMSS, St Albans, Vic, Australia

[7] Western Hlth, St Albans, Vic, Australia

[8] UConn Hlth, Div Endocrinol & Metab, Dept Med, Farmington, CT 06030 USA

来源：

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY | 2021年 / 69卷 / 05期

关键词：

osteoporosis; older adult; prevention; sarcopenia; VITAMIN-D SUPPLEMENTATION; SARC-F; UPDATED METAANALYSIS; RESISTANCE EXERCISE; VERTEBRAL FRACTURES; EWGSOP DEFINITION; MUSCLE STRENGTH; BONE-DENSITY; RISK-FACTORS; PREVALENCE;

D O I：

10.1111/jgs.17043

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Osteoporosis and sarcopenia are common in older adults. Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. Bone fractures can result in changes in posture, pain, the need for surgical repair and functional impairment. Sarcopenia is the progressive and generalized loss of skeletal muscle mass, strength and/or physical performance. Older adults with sarcopenia experience increased risk of frailty, disability, hospitalizations, mortality, and a reduced quality of life. In this narrative review we provide guidance regarding the prevention of both osteoporosis and sarcopenia, including interventions that prevent both conditions from occurring, recommended screening and treatment to prevent progression.

引用

页码：1388 / 1398

页数：11

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