Helicobacter pylori:: Factors affecting eradication and recurrence

Proton pump inhibitors play an important role in increasing the bioavailability of antibiotics in the gastric mucus by altering gastric volumes and increasing the stability of some antibiotics, e.g., clarithromycin. Increasing the doses of potent proton pump inhibitors has small effects on eradication rates but there may be differences between proton pump inhibitors that need further study.