A Nano-porous Aerogel Biochip for Molecular Recognition of Nucleotide Acids

被引：0
|
作者：
Li, Yen Kuang [1 ,2 ]
Yang, Den-Kai [3 ]
Chen, Yun-Chu [1 ,2 ]
Su, Hung-Ju [4 ]
Wu, Jui-Chuang [3 ]
Chen-Yang, Yui Whei [1 ,2 ]
机构：
[1] Chung Yuan Christian Univ, 200 Chung Pei Rd, Tao Yuan, Taiwan
[2] Chung Yuan Christian Univ, Dept Chem, Chungli 32023, Taoyuan County, Taiwan
[3] Chung Yuan Christian Univ, Dept Chem Engn, R&D Ctr Membrane Technol, Chungli 32023, Taiwan
[4] Ind Technol Res Inst, Ctr Biomed Engn, Hsinchu, Taiwan
来源：
MICRO-AND NANOSYSTEMS IN MEDICINE, ACTIVE IMPLANTS, BIOSENSORS | 2009年 / 25卷 / 08期
关键词：
Aerogel; molecular recognition; DNA detection; 3D biochips;
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
A nano-porous aerogel was produced in regular atmospheric conditions using the sol-gel polymerization of tetraethyl orthosilicate (TEOS) to build a three-dimensional (3D) structure for recognizing nucleotide acids. The Fourier transformation infrared spectroscopy and Brunauer-Emmett-Teller instrument had been used to characterize this 3D aerogel and concluded that it had a high porosity and large internal networking surface area to capture nucleotide acids. The functionality of molecular recognition on nucleotide acids was demonstrated on human gene ATP5O.
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页码：8 / +
页数：2
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