Synthesis of 3-alkyl substituted imidazo[1,5-a]pyridines under microwave irradiation

被引：0

作者：

Wang, Lai-Bao ^{[1
]}

Pan, Jia ^{[1
]}

Tang, Can-Lin ^{[1
]}

Jiang, Da-Wei ^{[1
]}

Qiu, Fei ^{[1
]}

Bu, Xiu-Ren ^{[2
]}

Wang, Jie ^{[1
]}

机构：

[1] Nanjing Univ, Coll Chem & Chem Engn, Nanjing 210093, Peoples R China

[2] Clark Atlanta Univ, Dept Chem, Atlanta, GA 30314 USA

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 27卷 / 12期

关键词：

microwave irradiation; imidazo[1,5-a]pyridine; synthesis;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Under regular heating or microwave irradiation, 3-alkyl substituted imidazo[1,5-a]pyridines were synthesized from 2,2'-pyridil or di-2-pyridyl ketone and aliphatic aldehydes in the presence of ammonium acetate and acetic acid. Compared to the traditional heating condition, 3-alkyl imidazo[1,5-a]pyridines were obtained with higher yields and shorter reaction time under microwave irradiation. All products were characterized by their H-1 NMR, MS spectra and elemental analysis.

引用

页码：1573 / 1576

页数：4

共 15 条

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