Emergence of Ertapenem Resistance in an Escherichia coli Clinical Isolate Producing Extended-Spectrum β-Lactamase AmpC

被引：18
|
作者：
Guillon, Helene [1 ,2 ]
Tande, Didier [3 ]
Mammeri, Hedi [1 ,2 ]
机构：
[1] Univ Amiens, Serv Bacteriol, Ctr Hosp, Hop Nord, F-80000 Amiens, France
[2] Univ Picardie Jules Verne, Fac Med Amiens, F-80000 Amiens, France
[3] Univ Brest, Microbiol Serv, Hop Morvan, Ctr Hosp, F-29609 Brest, France
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2011年 / 55卷 / 09期
关键词：
KLEBSIELLA-PNEUMONIAE; CEPHALOSPORINASES; EXPRESSION; GENES;
D O I：
10.1128/AAC.01513-10
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Escherichia coli isolate MEV, responsible for a bloodstream infection, was resistant to penicillins, cephalosporins, and ertapenem. Molecular and biochemical characterization revealed the production of a novel, chromosome-borne, extended- spectrum AmpC (ESAC) beta-lactamase with a Ser-282 duplication and increased carbapenemase activity. This study demonstrates for the first time that chromosome-borne ESAC beta-lactamases can contribute to the emergence of ertapenem resistance in E. coli clinical isolates.
引用
下载
收藏
页码：4443 / 4446
页数：4
相关论文
共 50 条
  • [1] In vitro emergence of ertapenem resistance in Escherichia coli producing extended-spectrum β-lactamase
    Villar, Hugo E.
    Jugo, Monica B.
    Visser, Matas
    Hidalgo, Mariana
    Hidalgo, Gabriel
    Cesar Maccallini, Gustavo
    REVISTA ESPANOLA DE QUIMIOTERAPIA, 2014, 27 (01) : 51 - 55
  • [2] Detection of Extended-spectrum β-lactamase and AmpC β-lactamase Producing Escherichia coli Isolates from Chickens
    Basaran Kahraman, Beren
    Diren Sigirci, Belgi
    Celik, Baran
    Gumus, Berna
    Metiner, Kemal
    Adiguzel, M. Cemal
    Bagcigil, A. Funda
    Ikiz, Serkan
    Ozgur, N. Yakut
    Ak, Seyyal
    KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, 2016, 22 (04) : 591 - 596
  • [3] Emergence of Escherichia coli producing extended-spectrum AmpC β-lactamases (ESAC) in animals
    Haenni, Marisa
    Chatre, Pierre
    Madec, Jean-Yves
    FRONTIERS IN MICROBIOLOGY, 2014, 5
  • [4] Extended-spectrum β-lactamase-producing Escherichia coli
    Huang, Ying
    Zeng, Li
    Doi, Yohei
    Lv, Luchao
    Liu, Jian-Hua
    LANCET INFECTIOUS DISEASES, 2020, 20 (04): : 404 - 405
  • [5] Wild Boars Carry Extended-Spectrum β-Lactamase- and AmpC-Producing Escherichia coli
    Holtmann, Anna R.
    Meemken, Diana
    Mueller, Anja
    Seinige, Diana
    Buettner, Kathrin
    Failing, Klaus
    Kehrenberg, Corinna
    MICROORGANISMS, 2021, 9 (02) : 1 - 13
  • [6] Fecal Colonization with Extended-Spectrum Beta-Lactamase and AmpC-Producing Escherichia coli
    Al-Agamy, Mohamed H.
    El Mahdy, Taghrid S.
    Shibl, Atef M.
    BIOMED RESEARCH INTERNATIONAL, 2016, 2016
  • [7] Prevalence of extended-spectrum and AmpC β-lactamase-producing Escherichia coli in Dutch dairy herds
    Heuvelink, Annet E.
    Gonggrijp, Maaike A.
    Buter, Rianne G. J.
    ter Bogt-Kappert, Carlijn C.
    van Schaik, Gerdien
    Velthuis, Annet G. J.
    Lam, Theo J. G. M.
    VETERINARY MICROBIOLOGY, 2019, 232 : 58 - 64
  • [8] Extended-spectrum β-lactamase producing Escherichia coli: changing epidemiology and clinical impact
    Oteo, Jesus
    Perez-Vazquez, Maria
    Campos, Jose
    CURRENT OPINION IN INFECTIOUS DISEASES, 2010, 23 (04) : 320 - 326
  • [9] Prevalence and Molecular Characteristics of Extended-Spectrum and AmpC β-Lactamase Producing Escherichia coli in Grazing Beef Cattle
    Lee, Shinyoung
    Teng, Lin
    DiLorenzo, Nicolas
    Weppelmann, Thomas A.
    Jeong, Kwangcheol Casey
    FRONTIERS IN MICROBIOLOGY, 2020, 10
  • [10] Prevalence and molecular characterization of extended-spectrum β-lactamase (ESBL) and plasmidic AmpC β-lactamase (pAmpC) producing Escherichia coli in dogs
    Aslantas, Ozkan
    Yilmaz, Ebru Sebnem
    JOURNAL OF VETERINARY MEDICAL SCIENCE, 2017, 79 (06): : 1024 - 1030
12345