Porous scaffold design using the distance field and triply periodic minimal surface models

被引:238
|
作者
Yoo, Dong J. [1 ]
机构
[1] Daejin Univ, Dept Comp Aided Mech Design Engn, Sundan Dong 487711, Pocheon Si, South Korea
关键词
Distance field; Triply periodic minimal surface; Tissue engineering; Porous scaffold design; TISSUE ENGINEERING SCAFFOLDS; MECHANICAL-PROPERTIES; FREEFORM FABRICATION; BONE; RECONSTRUCTION; STEREOLITHOGRAPHY; ARCHITECTURES; MESH; CT;
D O I
10.1016/j.biomaterials.2011.07.019
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
An effective method for the 3D porous scaffold design of human tissue is presented based on a hybrid method of distance field and triply periodic minimal surface (TPMS). By the creative application of traditional distance field algorithm into the Boolean operations of the anatomical model and TPMS-based unit cell library, an almost defects free porous scaffolds having the complicated micro-structure and high quality external surface faithful to a specific anatomic model can be easily obtained without the difficult and time-consuming trimming and re-meshing processes. After generating the distance fields for the given tissue model and required internal micro-structure, a series of simple modifications in distance fields enable us to obtain a complex porous scaffold. Experimental results show that the proposed scaffold design method has the potential to combine the perfectly interconnected pore networks based on the TPMS unit cell libraries and the given external geometry in a consistent framework irrespective of the complexity of the models. (C) 2011 Elsevier Ltd. All rights reserved.
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页码:7741 / 7754
页数:14
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