Antidiabetic activity of Phyllanthus sellowianus in Streptozotocin-induced diabetic rats

被引:6
|
作者
Hnatyszyn, O [1 ]
Mino, J [1 ]
Gorzalczany, S [1 ]
Ferraro, G [1 ]
Coussio, J [1 ]
Acevedo, C [1 ]
机构
[1] UNIV BUENOS AIRES,FAC FARM & BIOQUIM,CATEDRA FARMACOL,RA-1113 BUENOS AIRES,DF,ARGENTINA
关键词
Phyllanthus sellowianus; antidiabetic activity; aqueous extract;
D O I
10.1016/S0944-7113(97)80076-1
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The aqueous extract (5% w/v) of the stem barks of Phyllanthus sellowianus Muller Arg. (Euphorbiaceae) was administered orally at the dose of 4 ml/100 g body weight (corresponding to 2 g of dry plant material/kg body weight) to normal and streptozotocin-induced diabetic rats. Blood glucose was estimated 3 weeks after daily administration of the extract and was compared to the pre-treatment level. The results show that the administration of the extract significantly lowered the blood glucose in the diabetic rats.
引用
收藏
页码:251 / 253
页数:3
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