Discontinued drugs in 2008: oncology drugs

被引：18

作者：

Williams, Robert ^{[1
]}

机构：

[1] Canc Res UK, Drug Dev Off, London WC2A 3PX, England

来源：

EXPERT OPINION ON INVESTIGATIONAL DRUGS | 2009年 / 18卷 / 11期

关键词：

1D09C3; 4-demethylpenclomedine; ARQ-171; AZD-4992; CNF-1010; DN-101; FCE-28068; FCE-28069; folitixorin calcium; huMy9-6-DM4; INNO-305; mitumprotimut-T; MLN-8054; N-acetylcysteine; PD-0325901; phosphomannopentaose sulfate; PI-166; SGX-523; spisulosine; Symadex; tozasertib lactate; varalanib; zanolimumab; ATTRITION RATES;

D O I：

10.1517/13543780903151806

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The failure of drug candidates in clinical development remains a critical issue for the pharmaceutical and biotechnology industries. This article documents those oncology drugs discontinued in 2008 and briefly reviews reasons for termination of development. Source information was derived from a search of the Pharmaprojects database for drugs reaching phase I - III clinical trials.

引用

页码：1581 / 1594

页数：14

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