Highly Regioselective Palladium-Catalyzed Oxidative Coupling of Indolizines and Vinylarenes via C-H Bond Cleavage

被引：84
|
作者：
Yang, Yuzhu [1 ]
Cheng, Kai [1 ]
Zhang, Yuhong [1 ]
机构：
[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China
来源：
ORGANIC LETTERS | 2009年 / 11卷 / 24期
关键词：
HECK REACTION; DIRECT FUNCTIONALIZATION; DIRECT ARYLATION; ARYL BROMIDES; ALKENYLATION; ACTIVATION; OLEFINS; ALPHA; ACID; HETEROCYCLES;
D O I：
10.1021/ol902315w
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly regioselective oxidative coupling reaction between indolizines and vinylarenes has been accomplished in the presence of palladium catalysts to give only the branched a-product in high efficiency. The regioselectivity is promoted significantly by bidentate nitrogen ligands.
引用
收藏
页码：5606 / 5609
页数：4
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