Antimicrobial Stewardship in Pediatric Care: Strategies and Future Directions

被引：17

作者：

Newland, Jason G. ^{[1
,2
]}

Banerjee, Ritu ^{[3
,4
]}

Gerber, Jeffrey S. ^{[5
,6
]}

Hersh, Adam L. ^{[7
,8
]}

Steinke, Leah ^{[9
]}

Weissman, Scott J. ^{[10
,11
]}

机构：

[1] Childrens Mercy Hosp & Clin, Kansas City, MO 64108 USA

[2] Univ Missouri, Dept Pediat, Infect Dis Sect, Kansas City, MO USA

[3] Mayo Clin, Coll Med, Dept Pediat & Adolescent Med, Div Pediat Infect Dis, Rochester, MN USA

[4] Mayo Childrens Hosp, Rochester, MN USA

[5] Univ Penn, Dept Pediat, Div Infect Dis, Sch Med, Philadelphia, PA 19104 USA

[6] Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA

[7] Univ Utah, Dept Pediat, Div Infect Dis, Salt Lake City, UT USA

[8] Primary Childrens Med Ctr, Salt Lake City, UT 84103 USA

[9] Childrens Hosp Michigan, Dept Pharm, Detroit Med Ctr, Detroit, MI 48201 USA

[10] Univ Washington, Med Ctr, Dept Pediat, Div Infect Dis, Seattle, WA 98195 USA

[11] Seattle Childrens Hosp, Seattle, WA USA

来源：

PHARMACOTHERAPY | 2012年 / 32卷 / 08期

关键词：

antimicrobial stewardship; pediatrics; special populations; antibiograms; prospective audit with feedback; prior authorization; CLOSTRIDIUM-DIFFICILE INFECTION; ACADEMIC-MEDICAL-CENTER; RESPIRATORY-TRACT INFECTIONS; IN-HOSPITAL ANTIBIOGRAMS; ANTIBACTERIAL DRUG-USE; ANTIBIOTIC ORDER FORM; UNITED-STATES; PRESCRIBING PATTERNS; VANCOMYCIN USE; IMPACT;

D O I：

10.1002/j.1875-9114.2012.01155.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Antimicrobial stewardship programs (ASPs) are an effective strategy for improving the quality and safety of antimicrobial prescribing for hospitalized patients. Pediatric ASPs are in their early stages of development, and there are unique issues relevant to children. The imperative to ensure that antimicrobials are prescribed judiciously is highlighted by the ongoing epidemic increase in antimicrobial-resistant infections and the simultaneous decline in the rate of new drug development. In this review we describe the process of ASP development for pediatrics, review existing data regarding the impact of pediatric ASPs, and describe the priorities and challenges for ASP research including study design and appropriate end points.

引用

页码：735 / 743

页数：9

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