A NOVEL RESORCINOL DERIVATIVE FROM THE LEAVES OF Piper betle

被引：3
|
作者：
Atiya, Akhtar [1 ]
机构：
[1] Birla Inst Technol, Dept Pharmaceut Sci & Technol, Div Pharmacognosy & Phytochem, Ranchi 835215, Jharkhand, India
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2017年 / 53卷 / 04期
关键词：
Piper betle; resorcinol derivative; cytotoxic activity;
D O I：
10.1007/s10600-017-2070-8
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A novel resorcinol derivative characterized as 1-n-heptadecanyloxyresorcinol (1) has been isolated from the chloroform extract of the leaves of Piper betle var. haldia. Isolation was performed using the chromatographic method, and the structure was established based on spectroscopic data. Evaluation of cytotoxic activity against human oral cancer cell lines (AW13516 and AW8507) was conducted using SRB assay. Compound 1 showed moderate cytotoxic activity with GI(50) values of 25.0 and 31.8 mu g.mL(-1), respectively.
引用
收藏
页码：611 / 613
页数：3
相关论文
共 50 条
  • [1] A Novel Resorcinol Derivative from the Leaves of Piper betle
    Akhtar Atiya
    [J]. Chemistry of Natural Compounds, 2017, 53 : 611 - 613
  • [2] Novel Amides Derivative with Antimicrobial Activity of Piper betle var. nigra Leaves from Indonesia
    Prasetya, Fajar
    Salam, Supriatno
    Rahmadani, Agung
    Haikal, Kansy
    Febrina, Lizma
    Anshory, Hady
    Arifuddin, Muhammad
    Siregar, Vita Olivia
    Narsa, Angga Cipta
    Herman, Herman
    Ahmad, Islamudin
    Indriyanti, Niken
    Ibrahim, Arsyik
    Rusli, Rolan
    Rijai, Laode
    Kuncoro, Hadi
    [J]. MOLECULES, 2021, 26 (02):
  • [3] A phenylpropanoid dimer from the leaves of Piper betle
    Atiya, Akhtar
    Majrashi, Taghreed A.
    Begum, M. Yasmin
    Lal, Uma R.
    Sinha, Barij N.
    Qadira, Shaik Fayazuddin Abdul
    [J]. NATURAL PRODUCT RESEARCH, 2023, 37 (09) : 1550 - 1556
  • [4] The new ether derivative of phenylpropanoid and bioactivity was investigated from the leaves of Piper betle L.
    Atiya, Akhtar
    Sinha, Barij Nayan
    Lal, Uma Ranjan
    [J]. NATURAL PRODUCT RESEARCH, 2020, 34 (05) : 638 - 645
  • [5] Two New Sphingolipids from the Leaves of Piper betle L.
    Chen, Duo-Zhi
    Xiong, Hua-Bin
    Tian, Kai
    Guo, Jun-Ming
    Huang, Xiang-Zhong
    Jiang, Zhi-Yong
    [J]. MOLECULES, 2013, 18 (09) : 11241 - 11249
  • [6] Identification and Characterization of Pediococcus Species from Piper betle (Betel) Leaves
    C. Keerthana
    R. B. Narayanan
    [J]. Current Microbiology, 2021, 78 : 198 - 205
  • [7] Identification and Characterization of Pediococcus Species from Piper betle (Betel) Leaves
    Keerthana, C.
    Narayanan, R. B.
    [J]. CURRENT MICROBIOLOGY, 2021, 78 (01) : 198 - 205
  • [8] Determination of 4-Allyl Resorcinol and Chavibetol from Piper betle Leaves by Subcritical Water Extraction Combined with High-Performance Liquid Chromatography
    Musa, Taysir Abdelrhman
    Sanagi, Mohd Marsin
    Ibrahim, Wan Aini Wan
    Ahmad, Farediah
    Aboul-Enein, Hassan Y.
    [J]. FOOD ANALYTICAL METHODS, 2014, 7 (04) : 893 - 901
  • [9] Effects of Drying Methods on the Antioxidant Properties of Piper betle Leaves
    Ramarao, Kivaandra Dayaa Rao
    Razali, Zuliana
    Somasundram, Chandran
    Kunasekaran, Wijenthiran
    Jin, Tan Li
    [J]. MOLECULES, 2024, 29 (08):
  • [10] Piper betle leaves impairs masculine sexual behaviour of rats
    Ratnasooriya, HW
    Premakumara, GAS
    [J]. MEDICAL SCIENCE RESEARCH, 1996, 24 (05): : 303 - 306
12345