MEDICAL ONCOLOGY Optimizing chemotherapy and radiotherapy for anaplastic glioma

被引:32
|
作者
Morris, Patrick G.
Lassman, Andrew B. [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dept Neurol, New York, NY 10065 USA
关键词
PHASE-III; EUROPEAN ORGANIZATION; OLIGODENDROGLIOMA; SURVIVAL; TRIAL;
D O I
10.1038/nrclinonc.2010.98
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The optimum approach for the treatment of rare anaplastic gliomas following surgical resection is uncertain. A recent study has now provided a greater understanding of the heterogeneous tumor biology of these tumors and has emphasized the prognostic importance of chromosome 1p19q deletion, IDH mutation and MGMT promoter methylation. The importance of radiotherapy and chemotherapy for treating these heterogeneous tumors is being elucidated for subgroups of patients.
引用
收藏
页码:428 / 430
页数:4
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