The changes of electrolytes in serum and urine in children with neurally mediated syncope cured by oral rehydration salts

Objective: To detect the changes of electrolytes in serum and urine in children with nerve mediated syncope (NMS) cured by oral rehydration salts (ORS). Method: From May 2014 to April 2015, 135 patients with symptoms like unexplained syncope and presyncope were administrated in our hospital, including 60 boys and 75 girls, aged between 4 and 16 (10.2 +/- 2.7) years. After head-up tilt test (HUTT), their electrolytes in serum and urine were examined. Those who were positive to the HUTT received ORS and health education, while others were only treated by health education. With the period of subsequent visit arranging 21-154 (42.6 +/- 27.7) days, the improvement of their clinical manifestation were inquired and electrolytes in serum and urine were re-tested. Result: (1) The total effective percentage of ORS treatment was 63.0%, and the negative conversion rate of HUTT was 48.2%. (2) In the first time of visit to hospital, there was no statistical significance between the HUTT-positive and the HUTT-negative in serumelectrolytes, 24-h urine electrolytes and 24-h urine volume(P > 0.05). (3) In the return visit to hospital, the serum calcium and serum phosphorus in the HUTT-positive were higher than those in the HUTT-negative (P < 0.05). (4) With the intake of ORS, 24-h urine sodium, 24-h urine chlorine and 24-h urine volume were improved than pre-treatment (P < 0.05 or 0.01). Conclusion: ORS was an effective treatment to the NMS children, with 24-h urine volume and urine chloride increasing. (C) 2016 Elsevier Ireland Ltd. All rights reserved.