Acceptability of Preclinical Research on Nonhuman Primates in Reproductive Medicine: The Patient Perspective

被引:4
|
作者
Dancet, Eline A. F. [1 ]
Spiessens, Carl [1 ]
Vangenechten, Rebecca
Billiet, Jaak [2 ]
De Tavernier, Johan [3 ]
Welkenhuysen, Myriam [1 ]
D'Hooghe, Thomas M. [1 ,4 ,5 ]
机构
[1] Univ Louvain, Fertil Ctr, B-3000 Louvain, Belgium
[2] Univ Louvain, Ctr Sociol Res, B-3000 Louvain, Belgium
[3] Univ Louvain, Ctr Res Theol Eth, B-3000 Louvain, Belgium
[4] Natl Museums Kenya, Inst Primate Res, Nairobi, Kenya
[5] Gynecol & Obstet Invest, Louvain, Belgium
关键词
patient; animal experimentation; reproductive medicine; endometriosis; infertility; IN-VITRO FERTILIZATION; OVARIAN STIMULATION; PUBLIC-ATTITUDES; ANIMAL RESEARCH; BABOON; MODEL;
D O I
10.1177/1933719110380277
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The attitude of patients with reproductive disorders regarding the use of nonhuman primates (NHPs) in preclinical reproductive research and its determinants was examined. A survey was conducted on 299 patients with fertility problems and/or endometriosis in a European fertility center (RR=80%). The main outcome measure was the attitude toward reproductive research on NHPs. In total, 70.6% accept and 29.4% reject NHP research. Factors significantly positively related to acceptance are confidence in researchers and previous pregnancy. Factors significantly negatively related to acceptance include having a pet, membership of a nature organization, vegetarian, and having lived abroad. To the best of our knowledge, this study is the first on patients' perspective on NHP research. The majority of the patients accept reproductive research on NHPs. Trust in researchers was the most important positively related factor; therefore, researchers are advised to actively try to gain the trust of patients and the public.
引用
收藏
页码:70 / 78
页数:9
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