Background and objective: Intrathecal opioids are now used routinely in the UK for intra- and postoperative analgesia. The opioids of choice have altered over recent years and the dosage regimens used can vary between institutions. Concerns over safety have been reduced probably because much lower doses of opioids are now being used. This survey explored the practice of intrathecal opioid usage in the UK. Methods: We sent a questionnaire survey to 270 anaesthetic departments and received 199 replies, a response rate of 73.7%. Results: Intrathecal opioids were used in 175 (88.4%) departments. Of these departments, 107 (61.1%) had local guidelines or protocols in place. Opioids such as diamorphine (used in 136 (78.2%) of departments) and fentanyl (129 (74.1%)) with a shorter duration of action are now more commonly used than morphine (37 (21-3%)) for intrathecal analgesia. In 96 (54.5%) departments, patients were nursed on regular surgical wards following administration of spinal opioids. Conclusions: The use of low-dose lipophilic intrathecal opioids for postoperative analgesia is widespread in the UK. Patients are commonly nursed in low-dependency postanaesthetic care areas. The low incidence of adverse events reported by the respondents along with the popularity of the technique suggests that low-dose spinal opioid administration is safe.
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Dept. of Child Health, Queen's University of Belfast, Royal Maternity Hospital, BelfastDept. of Child Health, Queen's University of Belfast, Royal Maternity Hospital, Belfast
Craig J.S.
Tubman T.
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Dept. of Child Health, Queen's University of Belfast, Royal Maternity Hospital, BelfastDept. of Child Health, Queen's University of Belfast, Royal Maternity Hospital, Belfast
Tubman T.
McClure B.G.
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Dept. of Child Health, Queen's University of Belfast, Royal Maternity Hospital, BelfastDept. of Child Health, Queen's University of Belfast, Royal Maternity Hospital, Belfast
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Vanderbilt Univ, Med Ctr, Dept Anesthesiol, Div Pain Med, Nashville, TN USAVanderbilt Univ, Med Ctr, Dept Anesthesiol, Div Pain Med, Nashville, TN USA
Jackson, Tracy P.
Lonergan, Daniel F.
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Vanderbilt Univ, Med Ctr, Dept Anesthesiol, Div Pain Med, Nashville, TN USAVanderbilt Univ, Med Ctr, Dept Anesthesiol, Div Pain Med, Nashville, TN USA
Lonergan, Daniel F.
Todd, R. David
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Vanderbilt Univ, Med Ctr, Dept Anesthesiol, Div Pain Med, Nashville, TN USAVanderbilt Univ, Med Ctr, Dept Anesthesiol, Div Pain Med, Nashville, TN USA
Todd, R. David
Martin, Peter R.
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Vanderbilt Univ, Med Ctr, Dept Pharmacol & Psychiat, Nashville, TN USAVanderbilt Univ, Med Ctr, Dept Anesthesiol, Div Pain Med, Nashville, TN USA
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Leeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Lodh, Rajib
Amin, Sam
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Univ Hosp Bristol, Dept Paediat Neurol, Bristol, Avon, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Amin, Sam
Ammar, Amr
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Queens Med Ctr, Dept Paediat Neurosci, Nottingham, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Ammar, Amr
Bellis, Lucy
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Great North Childrens Hosp, Dept Paediat Neurol, Newcastle Upon Tyne, Tyne & Wear, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Bellis, Lucy
Brink, Phillip
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Tayside Childrens Hosp, Dept Paediat Neurol, Dundee, ScotlandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Brink, Phillip
Calisto, Amedeo
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John Radcliffe Hosp, Dept Paediat Neurosci, Oxford, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Calisto, Amedeo
Crimmins, Darach
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Temple St Childrens Univ Hosp, Dept Pediat Neurosurg, Dublin, IrelandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Crimmins, Darach
Eunson, Paul
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Royal Hosp Sick Children, Dept Paediat Neurol, Edinburgh, Midlothian, ScotlandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Eunson, Paul
Forsyth, Rob J.
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Great North Childrens Hosp, Dept Paediat Neurol, Newcastle Upon Tyne, Tyne & Wear, England
Newcastle Univ, Inst Neurosci, Newcastle Upon Tyne, Tyne & Wear, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Forsyth, Rob J.
Goodden, John
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Leeds Childrens Hosp, Leeds, W Yorkshire, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Goodden, John
Kaminska, Margaret
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Guys & St Thomas NHS Fdn Trust, Evelina Childrens Hosp, Complex Motor Disorder Serv, London, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Kaminska, Margaret
Kehoe, Joanne
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Cent Remedial Clin, Dept Paediat Neurol, Dublin, IrelandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Kehoe, Joanne
Kirkpatrick, Martin
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Tayside Univ Hosp NHS Trust, Dept Paediat Neurol, Dundee, ScotlandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
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Cent Remedial Clin, Dept Paediat Neurol, Dublin, IrelandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Leonard, Jane
Lording, Alice
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Southampton Childrens Hosp, Dept Paediat Neurol, Southampton, Hants, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Lording, Alice
Martin, Katherine
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Univ Nottingham Hosp, Dept Paediat Neurosci, Nottingham, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Martin, Katherine
Miller, Russell
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Great North Childrens Hosp, Dept Paediat Neurol, Newcastle Upon Tyne, Tyne & Wear, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Miller, Russell
Mordekar, Santosh R.
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Sheffield Childrens Hosp, Dept Paediat Neurol, Sheffield, S Yorkshire, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
机构:Leeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Whitney, Andrea
Vloeberghs, Michael
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机构:Leeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Vloeberghs, Michael
Zaki, Hesham
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Sheffield Teaching Hosp NHS Fdn Trust, Dept Neurosci, Sheffield, S Yorkshire, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England
Zaki, Hesham
Lumsden, Daniel E.
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Guys & St Thomas NHS Fdn Trust, Dept Paediat Neurosci, London, England
Kings Coll London, Fac Life Sci & Med, London, EnglandLeeds Childrens Hosp, Dept Paediat Neurosci, Leeds, W Yorkshire, England