Overcoming Barriers to Progress in Exercise Genomics

被引:42
|
作者
Bouchard, Claude [1 ]
机构
[1] Pennington Biomed Res Ctr, Human Genom Lab, Baton Rouge, LA 70808 USA
来源
EXERCISE AND SPORT SCIENCES REVIEWS | 2011年 / 39卷 / 04期
基金
美国国家卫生研究院;
关键词
exercise genomics; candidate genes; single nucleotide polymorphism; genome-wide association study; genomic predictors; INSULIN SENSITIVITY; GENE-EXPRESSION; HUMAN MUSCLE; PERFORMANCE; FITNESS; AGE; ASSOCIATION; RESPONSES; IMPACT; MAP;
D O I
10.1097/JES.0b013e31822643f6
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
BOUCHARD, C. Overcoming barriers to progress in exercise genomics. Exerc. Sports Sci. Rev., Vol. 39, No. 4, pp. 212-217, 2011. This commentary focuses on the issues of statistical power, the usefulness of hypothesis-free approaches such as in genome-wide association explorations, the necessity of expanding the research beyond common DNA variants, the advantage of combining transcriptomics with genomics, and the complexities inherent to the search for links between genotype and phenotype in exercise genomics research.
引用
收藏
页码:212 / 217
页数:6
相关论文
共 50 条
  • [1] Progress in xenotransplantation: overcoming immune barriers
    Sykes, Megan
    Sachs, David H.
    [J]. NATURE REVIEWS NEPHROLOGY, 2022, 18 (12) : 745 - 761
  • [2] Progress in xenotransplantation: overcoming immune barriers
    Megan Sykes
    David H. Sachs
    [J]. Nature Reviews Nephrology, 2022, 18 : 745 - 761
  • [3] Overcoming barriers to effective exercise programming
    Gallagher, KI
    Jakicic, JM
    [J]. ACSMS HEALTH & FITNESS JOURNAL, 2002, 6 (06) : 6 - 12
  • [4] Overcoming exercise barriers in older adults
    Dunlap, J
    Barry, HC
    [J]. PHYSICIAN AND SPORTSMEDICINE, 1999, 27 (11): : 69 - 75
  • [5] Why and how to prescribe exercise: Overcoming the barriers
    Fletcher, G
    Trejo, JF
    [J]. CLEVELAND CLINIC JOURNAL OF MEDICINE, 2005, 72 (08) : 645 - +
  • [6] Genomes for Nurses: Understanding and Overcoming Barriers to Nurses Utilizing Genomics
    Hines-Dowell, Stacy
    Mcnamara, Elizabeth
    Mostafavi, Roya
    Taylor, Leslie
    Harrison, Lynn
    Mcgee, Rose B.
    Blake, Alise K.
    Lewis, Sara
    Perrino, Melissa
    Mandrell, Belinda
    Nichols, Kim E.
    [J]. JOURNAL OF PEDIATRIC HEMATOLOGY-ONCOLOGY NURSING, 2024, 41 (02): : 140 - 147
  • [7] Progress in overcoming barriers to influenza immunization of pregnant women
    Read, Jennifer S.
    Riley, Laura
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2012, 207 (03) : S1 - S2
  • [8] Current Approaches to Studying Hallucinations: Overcoming Barriers to Progress
    Ford, Judith M.
    [J]. SCHIZOPHRENIA BULLETIN, 2017, 43 (01) : 21 - 23
  • [9] Overcoming barriers to implement exercise in the management of hypertensive patients
    Cornelissen, V. A.
    [J]. BLOOD PRESSURE, 2023, 32 (01)
  • [10] Company-wide carbon targets: overcoming barriers to progress
    [J]. Structural Engineer, 2022, 100 (01): : 21 - 23