Ring-closing metathesis: A facile construct for alkaloid synthesis

被引：18

作者：

Martin, SF ^{[1
]}

机构：

[1] Univ Texas, Dept Chem & Biochem, Austin, TX 78712 USA

来源：

PURE AND APPLIED CHEMISTRY | 2005年 / 77卷 / 07期

关键词：

ring-closing metathesis; alkaloids; enantioselective; heterocycles; stereoselective;

D O I：

10.1351/pac200577071207

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ring-closing metathesis has been found to be a highly effective reaction for the synthesis of functionalized, bridged nitrogen heterocycles. The utility of the process has been established in several case studies, including a facile synthesis of the tropane ring system and efficient, enantioselective syntheses of the natural products (-)-peduncularine and (+)-anatoxin-a.

引用

页码：1207 / 1212

页数：6

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