Association between delirium prediction scores and days spent with delirium

Purpose: To determine the correlation and discriminative value of the E -PRE-DELIRIC and PRE-DELIRIC scores with delirium exposure to evaluate the prognostic value of both models. Methods: A secondary analysis of a randomized clinical trial enrolling 1506 delirium -free, critically ill adults with an anticipated ICU stay of _2 days. Days spent with delirium (>_1 positive CAM -ICU) or coma (>_1 RASS ?-4) in the 28 -days after ICU admission were calculated. Patients were categorized into four groups: no delirium, short - exposure (1 delirium day), moderate -exposure (2 -5 delirium days), and long- exposure (>_6 delirium days) to determine the correlation and discriminative value of the E -PRE-DELIRIC and the PRE-DELIRIC with days spent with delirium. Results: The correlation between the overall E-PRE-DELIRIC and PRE-DELIRIC scores and days spent with delirium were: R = 0.08 ( P = .005) and R = 0.26 ( P < .001), respectively. The correlation between both prediction scores and days spent with coma or delirium were R = 0.21 ( P < .0001) and R = 0.46 (P < .0001), respectively. The highest Area Under the Receiver Operating Characteristic for both E -PRE-DELIRIC [0.57 (95% CI:0.51 -0.62)] and PR E -DELIRIC [0.58 (95% CI:0.53 -0.62)] was found in the long delirium exposure group. Conclusion: The E-PRE-DELIRIC and PRE-DELIRIC model each poorly correlate and discriminate with days spent with delirium in the 28 days after ICU admission. ? 2020 Published by Elsevier Inc.