Stereotactic Body Radiotherapy for Pulmonary Oligometastases from Esophageal Cancer: Results and Prognostic Factors

被引:17
|
作者
Yamamoto, Takaya [1 ]
Niibe, Yuzuru [2 ,3 ]
Matsumoto, Yasuo [4 ]
Dekura, Yasuhiro [5 ]
Oh, Ryoong-Jin [6 ]
Yamashita, Hideomi [7 ]
Kakuhara, Hisao [8 ]
Aoki, Masahiko [9 ]
Jingu, Keiichi [1 ]
机构
[1] Tohoku Univ, Grad Sch Med, Dept Radiat Oncol, Sendai, Miyagi, Japan
[2] Toho Univ, Omori Med Ctr, Dept Radiol, Tokyo, Japan
[3] Okayama Univ, Dept Primary Care & Med Educ, Okayama, Japan
[4] Niigata Canc Ctr, Dept Radiat Oncol, Niigata, Japan
[5] Keiyu Kai Sapporo Hosp, Dept Radiat Oncol, Sapporo, Hokkaido, Japan
[6] Miyakojima IGRT Clin, Dept Radiat Oncol, Osaka, Japan
[7] Univ Tokyo, Dept Radiol, Tokyo, Japan
[8] Iwate Med Univ Hosp, Dept Radiol, Morioka, Iwate, Japan
[9] Hirosaki Univ, Dept Radiat Oncol, Hirosaki, Aomori, Japan
关键词
Stereotactic body radiotherapy (SBRT); oligometastases; oligo-recurrence; esophageal cancer; prognostic factor; OLIGO-RECURRENCE; RADIATION-THERAPY; MULTIMODALITY THERAPY; LUNG METASTASES; OUTCOMES;
D O I
10.21873/anticanres.14164
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background/Aim: The aim of this multi-center retrospective study was to investigate the results of stereotactic body radiotherapy (SBRT) for pulmonary oligometastases from esophageal cancer. Patients and Methods: Oligometastases from the esophagus were identified from a dataset of a Japanese survey. The Kaplan-Meier method and Cox regression were applied to perform analyses. Results: A total of 114 patients with 132 pulmonary oligometastases were collected. The 3-year local control rate, freedom from further metastasis (FFFM) rate and overall survival (OS) rate were 70.2%, 25.3% and 37.5%, respectively. Performance status (PS) (PS 1 vs. PS 0, p<0.01), disease-free interval (p=0.03) and history of local therapy for metastasis (p=0.01) had significant relationships with FFFM and only PS was an independent prognostic factor for OS (PS 1 vs. PS 0, p=0.02; PS 2-3 vs. PS 0, p=0.04). Conclusion: SBRT for pulmonary oligometastases from esophageal cancer provided good local control and survival.
引用
收藏
页码:2065 / 2072
页数:8
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