Because of recent upsurges in medical costs, health plans, employers, and the government will increasingly demand solutions that stretch performance boundaries with regard to quality of care, provider and member satisfaction, and near term cost benefits. The health management industry is awakening to three trends that will revolutionize the way we provide healthcare: (i) what we look with and what we look for determines how we view health and subsequently how we choose interventions and solution sets; (ii) finding the people we can help requires us to broaden our thinking to include non-disease-based factors as drivers of care-seeking behavior; and (iii) the convergence of new knowledge and new technologies sets the stage for disruptive innovation in the way care is delivered, thereby providing an unprecedented opportunity to extend performance boundaries. This article details the rationale behind the three trends listed above, which are shaking the traditional foundations of health management and which, taken together, will usher in a dramatic improvement in quality of care and financial outcomes for entities that manage the health and care of populations.