Remission of Cushing's disease with growth hormone replacement

被引：0
|
作者：
Ozturk, Mustafa [1 ]
Atmaca, Murat [1 ]
机构：
[1] Yuzuncu Yil Univ, Fac Med, Internal Med Dept Endocrinol & Metab, Van, Turkey
来源：
GROWTH HORMONE & IGF RESEARCH | 2011年 / 21卷 / 04期
关键词：
Cushing's disease; Growth hormone; 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1; THERAPY; DEFICIENCY; CORTISOL; ADULTS;
D O I：
10.1016/j.ghir.2011.05.005
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Treatment of Cushing's disease is often challenging. The success rates are not satisfactory and therapeutic interventions frequently causes hypopituitarism. We present three cases of remitting Cushing's disease complicated with growth hormone deficiency. Surprisingly, growth hormone replacement resulted in complete clinical and laboratory remission of Cushing's disease in these patients. However, one of the patients died of myocardial infarction. Effects of growth hormone on cortisol metabolism are discussed. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：238 / 241
页数：4
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