In-situ detection of DNA hybridization with a microfiber Bragg grating biosensor

被引：0
|
作者：
Sun, Dandan [1 ]
Guo, Tuan [1 ]
Xie, Xiaodong [1 ]
Ran, Yang [1 ]
Huang, Yunyun [1 ]
Guan, Bai-Ou [1 ]
机构：
[1] Jinan Univ, Inst Photon Technol, Guangzhou 510632, Guangdong, Peoples R China
来源：
23RD INTERNATIONAL CONFERENCE ON OPTICAL FIBRE SENSORS | 2014年 / 9157卷
关键词：
Biosensors; Microfiber Bragg gratings (mFBG); DNA; Poly-L-lysine (PLL);
D O I：
10.1117/12.2059433
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Microfiber Bragg gratings (mFBGs) can be used as cost-effective and relatively simple-to-implement biosensors for monitoring DNA interactions in situ. The sensors are functionalized by a monolayer of poly-L-lysine (PLL) with the specific molecular recognition probe DNA sequences to bind with high specificity to a given target. By recording the wavelength seperation between the two resonant peaks of a single mFBG, the mFBG biosensor is capable of detecting the presence of specific target DNA in situ.
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页数：4
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