Two triterpene saponins from Achyranthes bidentata

被引：32
|
作者：
Mitaine-Offer, AC
Marouf, A
Hanquet, B
Birlirakis, N
Lacaille-Dubois, MA
机构：
[1] Univ Bourgogne, Fac Pharm, Unite MIB, Lab Pharmacognosie, F-21079 Dijon, France
[2] Univ Oran, Fac Sci, Dept Biol, Oran, Algeria
[3] Univ Bourgogne, CNRS UMR 5632, Lab Synth & Electrosynth Organomet, F-21004 Dijon, France
[4] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2001年 / 49卷 / 11期
基金：
美国国家科学基金会;
关键词：
Achyranthes bidentata; Amaranthaceae; triterpene-saponin;
D O I：
10.1248/cpb.49.1492
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Bidentatoside II (1) and chikusetsusaponin V methyl ester (2) are two further triterpene saponins isolated from the roots of Achyranthes bidentata. Chemical and homo and heteronuclear two-dimensional (2D) NMR techniques have led to the structural elucidation of 1 which is a new seco-glycoside of oleanolic acid and the full H-1- and C-13-NMR assignments of 2. These compounds did not show any potentiation of the in vitro cytotoxicity of cisplatin in the HT 29 human colon cancer cell line.
引用
收藏
页码：1492 / 1494
页数：3
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