Transcriptional and Metabolic Profiling Reveals Alpha-Ketoglutarate As a Novel Mediator of Aberrant Platelet Activity and Inflammation in Myeloproliferative Neoplasms

被引:0
|
作者
He, Fan [1 ]
Laranjeira, Angelo Ba [1 ]
Kong, Tim [1 ]
Bark, Katrina [2 ]
Liu, Alice [2 ]
Allen, Maggie J. [1 ]
Fisher, Daniel Ac [1 ]
Fulbright, Mary [1 ]
Yu, LaYow [1 ]
Lasky, Nina M. [2 ]
Sykes, Stephen M. [3 ]
D'Alessandro, Angelo [4 ]
Di Paola, Jorge [2 ]
Oh, Stephen T. [5 ]
机构
[1] Washington Univ, Sch Med, Div Hematol, St Louis, MO USA
[2] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA
[3] Washington Univ, Dept Pediat, St Louis, MO 63130 USA
[4] Univ Colorado, Sch Med, Dept Biochem & Mol Genet, Aurora, CO USA
[5] Washington Univ, Sch Med, Siteman Canc Ctr, St Louis, MO USA
关键词
D O I
10.1182/blood-2022-167786
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1095 / 1097
页数:3
相关论文
共 2 条
  • [1] Multiomic profiling reveals metabolic alterations mediating aberrant platelet activity and inflammation in myeloproliferative neoplasms
    He, Fan
    Laranjeira, Angelo B. A.
    Kong, Tim
    Lin, Shuyang
    Ashworth, Katrina J.
    Liu, Alice
    Lasky, Nina M.
    Fisher, Daniel A. C.
    Cox, Maggie J.
    Fulbright, Mary C.
    Antunes-Heck, Lilian
    Yu, Layow
    Brakhane, Molly
    Gao, Bei
    Sykes, Stephen M.
    D'Alessandro, Angelo
    Di Paola, Jorge
    Oh, Stephen T.
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2024, 134 (03):
  • [2] In Vivo Transcriptional Profiling of Yersinia pestis Reveals a Novel Bacterial Mediator of Pulmonary Inflammation
    Pechous, Roger D.
    Broberg, Christopher A.
    Stasulli, Nikolas M.
    Miller, Virginia L.
    Goldman, William E.
    [J]. MBIO, 2015, 6 (01):