Pharmacologic Management of Excessive Daytime Sleepiness

被引:9
|
作者
Takenoshita, Shinichi [1 ]
Nishino, Seiji [1 ]
机构
[1] Stanford Univ, Sleep & Circadian Neurobiol Lab, Dept Psychiat & Behav Sci, Sch Med, Palo Alto, CA 94304 USA
关键词
Stimulants; Excessive daytime sleepiness; Narcolepsy; Idiopathic hypersomnia; THYROTROPIN-RELEASING-HORMONE; ADMINISTERED SODIUM OXYBATE; TRAUMATIC BRAIN-INJURY; DOUBLE-BLIND; IDIOPATHIC HYPERSOMNIA; HYPOCRETIN-1; OREXIN; RANDOMIZED-TRIAL; LATENCY TEST; NARCOLEPSY-CATAPLEXY; PRACTICE PARAMETERS;
D O I
10.1016/j.jsmc.2020.02.006
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Excessive daytime sleepiness (EDS) is related to medical and social problems, including mental disorders, physical diseases, poor quality of life, and so forth. According to the International Classification of Sleep Disorders, Third Edition, diseases that result from EDS are narcolepsy type 1, narcolepsy type 2, idiopathic hypersomnia, hypersomnia due to a medical disorder, and others. EDS is usually treated using amphetamine-like central nervous system stimulants or modafinil and its R-enantiomer, armodafinil, wake-promoting compounds unrelated to amphetamines; a variety of new drugs are under development. The side effects of some stimulants are potent, and careful selection and management are required.
引用
收藏
页码:177 / +
页数:19
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