Autres approches en depistage du cancer du sein

被引:0
|
作者
Veron, Lucie [1 ]
Wehrer, Delphine [2 ]
Caron, Olivier [2 ]
Balleyguier, Corinne [3 ]
Delaloge, Suzette [1 ]
机构
[1] Inst Gustave Roussy, Dept Oncol Med, Programme Intercept Prevent Personnalisee Canc, Villejuif, France
[2] Inst Gustave Roussy, Dept Oncol Med, Serv Oncogenet, Villejuif, France
[3] Inst Gustave Roussy, Dept Oncol Med, Serv Radiol, Villejuif, France
关键词
Highriskofbreastcancer; Personalizedscreening; Risk-basedscreening; BREAST-CANCER; RISK; DENSITY; BENEFITS; EUROPE; HARMS;
D O I
10.1016/j.bulcan.2022.02.006
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
French breast cancer screening is based on organized screening with a mammography every two years for women between 50 and 74, and individualized screening for women at high or very high risk of breast cancer (personal history of breast cancer or atypical breast lesion or thoracic radiotherapy before the age of 25, high family risk without genetic mutation, genetic mutation). A novel approach of risk-based breast cancer screening is currently under evaluation in many countries, including France. This personalized screening, based on individual risk of having breast cancer in the next years, uses algorithms which combine clinical parameters, mammographic density, familial history and genomic (using polygenic risk score), to estimate breast cancer risk and adapt screening's frequency.
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页码:786 / 794
页数:9
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