Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by Cu(II)-imine complex

被引:8
|
作者
Wan, Ning Ning [1 ,2 ]
Yang, Yong Lei [1 ,2 ]
Wang, Wen Ping [1 ,2 ]
Xie, Zheng Feng [1 ]
Wang, Ji De [2 ]
机构
[1] Xinjiang Univ, Coll Chem & Chem Engn, Urumqi 830046, Peoples R China
[2] Xinjiang Univ, Minist Educ, Key Lab Oil & Gas Fine Chem, Urumqi 830046, Peoples R China
基金
中国国家自然科学基金;
关键词
Friedel-Crafts alkylation; Indole; Nitroalkene; Copper; Imine; MICHAEL ADDITION; PRACTICAL SYNTHESIS; FACILE SYNTHESIS; BIS(INDOLYL)ALKANES; PYRROLE; ACID;
D O I
10.1016/j.cclet.2011.04.013
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of new ligands L-1-L-7 were readily prepared in one step. Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by a novel Cu(II)-L complex has been developed. The remarkable advantages of this reaction are mild reaction conditions, simple workup procedure, high yields of products and the use of ethanol as a green solvent. (C) 2011 Ji De Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码:1155 / 1158
页数:4
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