Hepatopulmonary Syndrome and Portopulmonary Hypertension Implications for Liver Transplantation

被引：26

作者：

Lqbal, Shaz ^{[1
]}

Smith, Kern Akaya ^{[2
]}

Khungar, Vandana ^{[3
]}

机构：

[1] Hosp Univ Penn, Dept Med, Div Gen Internal Med, 3400 Spruce St, Philadelphia, PA 19104 USA

[2] Univ Penn, Perelman Sch Med, Dept Med, Pulm Allergy & Crit Care Div, 3400 Spruce St,834 West Gates Bldg, Philadelphia, PA 19104 USA

[3] Univ Penn, Perelman Sch Med, Div Gastroenterol & Hepatol, Dept Med, 3400 Spruce St 2 Dulles, Philadelphia, PA 19104 USA

来源：

CLINICS IN CHEST MEDICINE | 2017年 / 38卷 / 04期

关键词：

Cirrhosis; Hepatopulmonary; Portopulmonary; Transplant; EXHALED NITRIC-OXIDE; PULMONARY ARTERIAL-HYPERTENSION; QUALITY-OF-LIFE; PRACTICE GUIDELINE; INHALED ILOPROST; MELD EXCEPTION; SURVIVAL; OXYGENATION; CIRRHOSIS; PENTOXIFYLLINE;

D O I：

10.1016/j.ccm.2017.08.002

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Hepatopulmonary syndrome (HPS) and portopulmonary hypertension (PoPH) represent serious pulmonary complications of advanced liver diseases. Orthotopic liver transplantation (OLT) is capable of completely resolving the underlying abnormalities associated with HPS. On the other hand, post-OLT response in patients with PoPH is less predictable, although heavily influenced by pre-OLT mean pulmonary arterial pressure. It remains the case that the opportunity to reverse 2 potentially fatal organ dysfunctions in the liver and the lung makes HPS and PoPH more than worthy for further clinical investigations.

引用

页码：785 / +

页数：13

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