In vitro antibacterial activity of enrofloxacin and ciprofloxacin in combination against Escherichia coli and staphylococcal clinical isolates from dogs

被引：15
|
作者：
Lautzenhiser, SJ [1 ]
Fialkowski, JP [1 ]
Bjorling, D [1 ]
Rosin, E [1 ]
机构：
[1] Univ Wisconsin, Sch Vet Med, Madison, WI USA
来源：
RESEARCH IN VETERINARY SCIENCE | 2001年 / 70卷 / 03期
关键词：
D O I：
10.1053/rvsc.2001.0466
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The objective of the study was to determine the in vitro interaction between enrofloxacin and ciprofloxacin against Escherichia coli and staphylococcal isolates from dogs. The microdilution checkerboard assay was used to determine the interaction of the drugs against 50 E coli and 50 P-haemolytic staphylococcal clinical isolates. The checkerboard assay revealed that the activity of enrofloxacin and ciprofloxacin was additive against E coli and staphylococcal clinical isolates. It was concluded that for bacterial species against which ciprofloxacin is more potent than enrofloxacin, the in vivo transformation of enrofloxacin to ciprofloxacin may enhance the efficacy of enrofloxacin, if additivity of the drugs is confirmed in vivo. (C) 2001 Harcourt Publishers Ltd.
引用
收藏
页码：239 / 241
页数：3
相关论文
共 50 条
  • [1] In vitro activity of meropenem in combination with ciprofloxacin against clinical isolates of Pseudomonas aeruginosa
    Solak, S
    Willke, A
    Ergönül, Ö
    Tekeli, E
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2005, 25 (02) : 181 - 182
  • [2] In vitro activity of cefditoren against clinical isolates of Escherichia coli from a Korean hospital
    Ko, Kwan Soo
    Suh, Ji Yoeun
    Lee, Mi Young
    Lee, Nam Yong
    Peck, Kyong Ran
    Kwon, Ki Tae
    Jung, Dong Sik
    Song, Jae-Hoon
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2007, 30 (03) : 283 - 285
  • [3] In vitro bactericidal activity of enrofloxacin against gyrA mutant and qnr-containing Escherichia coli isolates from animals
    Cengiz, M.
    Sahinturk, P.
    Sonal, S.
    Buyukcangaz, E.
    Sen, A.
    Arslan, E.
    [J]. VETERINARY RECORD, 2013, 172 (18) : 474 - +
  • [4] IN-VITRO ACTIVITY OF ZIDOVUDINE ALONE AND IN COMBINATION WITH CIPROFLOXACIN AGAINST SALMONELLA AND ESCHERICHIA-COLI
    MASCELLINO, MT
    IONA, E
    IEGRI, F
    DEGREGORIS, P
    FARINELLI, S
    [J]. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 1993, 7 (01): : 23 - 28
  • [5] In vitro activity of trovafloxacin versus ciprofloxacin against clinical isolates
    Verbist, L
    Verhaegen, J
    [J]. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1996, 15 (08) : 683 - 685
  • [6] Comparative in vitro killing activities of enrofloxacin when used alone and in combination with doxycycline against E-coli isolates from dogs and cats
    Kireewan, Supapatt
    Suanpairintr, Nipattra
    [J]. THAI JOURNAL OF VETERINARY MEDICINE, 2017, 47 (02): : 217 - 224
  • [7] Remarkable antibiofilm activity of ciprofloxacin, cefoxitin, and tobramycin, by themselves or in combination, against enteroaggregative Escherichia coli in vitro
    Guerrieri, Caroline Gastaldi
    Goncalves, Mariana Teixeira
    da Silva, Anazi Ferreira
    dos Santos, Andre Luis Souza
    dos Santos, Kenia Valeria
    Spano, Liliana Cruz
    [J]. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2023, 107 (03)
  • [8] In Vitro Activity of Methyl Gallate Isolated from Galla Rhois Alone and in Combination with Ciprofloxacin Against Clinical Isolates of Salmonella
    Choi, Jang-Gi
    Kang, Ok-Hwa
    Lee, Young-Seob
    Oh, You-Chang
    Chae, Hee-Sung
    Jang, Hye-Jin
    Kim, Jong Hak
    Sohn, Dong-Hwan
    Shin, Dong-Won
    Park, Hyun
    Kwon, Dong-Yeul
    [J]. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2008, 18 (11) : 1848 - 1852
  • [9] In vitro activity of azithromycin in combination with amikacin, ceftazidime, ciprofloxacin or imipenem against clinical isolates of Acinetobacter baumannii
    Fermández-Cuenca, F
    Martínez-Martínez, L
    Pascual, A
    Perea, EJ
    [J]. CHEMOTHERAPY, 2003, 49 (1-2) : 24 - 26
  • [10] The in vitro Antibacterial Activity of Enrofloxacin-Trimethoprim Combination against Five Bacterial species
    Choi, Myung-Jin
    Yohannes, Sileshi Belew
    Lee, Seung-Jin
    Damte, Dereje
    Reza, Md. Ahsanur
    Rhee, Man-Hee
    Kim, Tae-Han
    Park, Seung-Chun
    [J]. PAKISTAN VETERINARY JOURNAL, 2012, 32 (03) : 363 - 366
12345