A non-enzymatic voltammetric xanthine sensor based on the use of platinum nanoparticles loaded with a metal-organic framework of type MIL-101(Cr). Application to simultaneous detection of dopamine, uric acid, xanthine and hypoxanthine

被引：97

作者：

Zhang, Li ^{[1
]}

Li, Shaobin ^{[1
,2
]}

Xin, Jianjiao ^{[1
]}

Ma, Huiyuan ^{[1
]}

Pang, Haijun ^{[1
]}

Tan, Lichao ^{[1
]}

Wang, Xinming ^{[1
]}

机构：

[1] Harbin Univ Sci & Technol, Coll Chem & Environm Engn, Sch Mat Sci & Engn, Harbin 150040, Heilongjiang, Peoples R China

[2] Qiqihar Univ, Heilongjiang Prov Key Lab Polymer Composite Mat, Coll Mat Sci & Engn, Qiqihar 161006, Peoples R China

来源：

MICROCHIMICA ACTA | 2019年 / 186卷 / 01期

关键词：

Metal-organic frameworks; Metal nanoparticles; Electrochemistry; Non-enzymatic sensor; Glassy carbon electrode; Cyclic voltammetry; Differential pulse voltammetry; Electrochemical impedance spectroscopy; Human serum; Standard addition method; SENSITIVE ELECTROCHEMICAL SENSOR; REDUCED GRAPHENE OXIDE; MODIFIED-ELECTRODE; PASTE ELECTRODE; BIOSENSOR; NANOCOMPOSITE; PERFORMANCE; SELECTIVITY; FABRICATION; OXIDATION;

D O I：

10.1007/s00604-018-3128-4

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A Cr-based metal-organic framework MIL-101(Cr) was used to load platinum nanoparticles (PtNPs) that were placed on a glassy carbon electrode (GCE). The modified GCE was used as a non-enzymatic xanthine sensor. Compared to bare GCE, it requires a strongly decreased working potential and an increased signal current for xanthine oxidation. This is due to the crystalline ordered structure and large specific surface of the MIL-101(Cr), and to the high conductivity of the Pt NPs. Differential pulse voltammetry (DPV) shows the sensor to have a wide linear range (0.5 - 162M), a low detection limit (0.42M), and high selectivity. It was applied to the simultaneous determination of dopamine, uric acid, xanthine and hypoxanthine at working potentials of 0.13, 0.28, 0.68 and 1.05V, respectively (vs. Ag/AgCl) and to quantify xanthine in spiked serum samples.

引用

页数：10

共 3 条

[1] A non-enzymatic voltammetric xanthine sensor based on the use of platinum nanoparticles loaded with a metal-organic framework of type MIL-101(Cr). Application to simultaneous detection of dopamine, uric acid, xanthine and hypoxanthine
Li Zhang
Shaobin Li
Jianjiao Xin
Huiyuan Ma
Haijun Pang
Lichao Tan
Xinming Wang
Microchimica Acta, 2019, 186
[2] A hydrogel composite prepared from alginate, an amino-functionalized metal-organic framework of type MIL-101(Cr), and magnetite nanoparticles for magnetic solid-phase extraction and UHPLC-MS/MS analysis of polar chlorophenoxy acid herbicides
Tan, Sze Chieh
Lee, Hian Kee
MICROCHIMICA ACTA, 2019, 186 (08)
[3] A hydrogel composite prepared from alginate, an amino-functionalized metal-organic framework of type MIL-101(Cr), and magnetite nanoparticles for magnetic solid-phase extraction and UHPLC-MS/MS analysis of polar chlorophenoxy acid herbicides
Sze Chieh Tan
Hian Kee Lee
Microchimica Acta, 2019, 186

← 1 →