Paediatric results of a surveillance study evaluating adverse effects of antiepileptic drugs

被引:0
|
作者
Steinborn, B. [1 ]
Buyle, S. [2 ]
Baukens, C. [2 ]
Edrich, P. [2 ]
De la Loge, C. [3 ]
机构
[1] Univ Med Sci, Dept Dev Neurol, Poznan, Poland
[2] UCB Pharma SA, Global Med Affairs CNS, Brussels, Belgium
[3] UCB Pharma SA, Global Hlth Outcomes Res, Braine Lalleud, Belgium
关键词
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
This observational, cross-sectional, non-interventional study explored the incidence and type of adverse effects (AEs) in patients with epilepsy treated with antiepileptic drugs (AEDs), using a standardised AE questionnaire. In the paediatric subpopulation (4-<16 years; N=255), 63.9% reported >= 1 AE. Fewer children on newer AEDs reported >= 1 AE than those on older AEDs (OR 0.43; 95% CI 0.20-0.94; P=0.035). Treatment modification occurred for 21.2% at study visit and was more likely in children reporting AEs and those with seizure(s) in the past year.
引用
收藏
页码:77 / +
页数:2
相关论文
共 50 条
  • [1] ADVERSE EFFECTS OF NEWER AND OLDER ANTIEPILEPTIC DRUGS IN PATIENTS WITH EPILEPSY: A POPULATION SURVEILLANCE STUDY
    Cramer, Joyce
    Striano, P.
    Baukens, C.
    Edrich, P.
    Buyle, S.
    [J]. EPILEPSIA, 2008, 49 : 97 - 97
  • [2] ADVERSE EFFECTS OF NEWER AND OLDER ANTIEPILEPTIC DRUGS IN PATIENTS WITH EPILEPSY: A POPULATION SURVEILLANCE STUDY
    Striano, P.
    Cramer, J.
    Hlinkova, L.
    Bergmann, A.
    Baukens, C.
    Edrich, P.
    Buyle, S.
    [J]. EPILEPSIA, 2009, 50 : 112 - 112
  • [3] THE ADVERSE EFFECTS OF ANTIEPILEPTIC DRUGS
    Bozkurt, D.
    Karamanli, Y.
    Guveli, B. Tekin
    Senadim, S.
    Yayla, V. A.
    [J]. EPILEPSIA, 2015, 56 : 214 - 215
  • [4] Adverse Effects of Antiepileptic Drugs
    Kwon, Oh-Young
    [J]. JOURNAL OF THE KOREAN MEDICAL ASSOCIATION, 2005, 48 (06): : 571 - 578
  • [5] Adverse effects of antiepileptic drugs
    Perucca, E
    Meador, KJ
    [J]. ACTA NEUROLOGICA SCANDINAVICA, 2005, 112 : 30 - 35
  • [6] Adverse effects of antiepileptic drugs
    Greenwood, RS
    [J]. EPILEPSIA, 2000, 41 : S42 - S52
  • [7] Adverse effects of antiepileptic drugs
    Luciano, DJ
    [J]. EPILEPSY AND DEVELOPMENTAL DISABILITIES, 2002, : 331 - 345
  • [8] Adverse effects of antiepileptic drugs
    Toledano, Rafael
    Gil-Nagel, Antonio
    [J]. SEMINARS IN NEUROLOGY, 2008, 28 (03) : 317 - 327
  • [9] Adverse effects of antiepileptic drugs
    Perucca, Piero
    Gilliam, Frank G.
    [J]. LANCET NEUROLOGY, 2012, 11 (09): : 792 - 802
  • [10] Cognitive adverse effects of antiepileptic drugs
    Milovanovic, M.
    Radivojevic, V.
    Jovanovic, M.
    Buder, N.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2019, 26 : 621 - 621