Calorie Restriction with or without Time-Restricted Eating in Weight Loss

To the Editor: Liu et al. (April 21 issue)(1) found no cardiometabolic differences with time-restricted eating as compared with daily caloric restriction. Yet, some possible benefits with time-restricted eating should not be dismissed, particularly if these could restore circadian rhythm(2) in the context of Westernized feeding patterns (i.e., daily duration of food intake frequently >15 hours per day, with >35% of daily calories consumed after 6 p.m.(3)) and a resultant increase in cardiovascular risk (e.g., increased blood pressure, impaired autonomic balance, or proinflammatory status).(4) Reductions in the time frame for food intake (from >= 14 hours per day to 10 to . . .