Cyclooctyne [60]fullerene hexakis adducts: a globular scaffold for copper-free click chemistry

被引：18

作者：

Ramos-Soriano, Javier ^{[1
,2
]}

Reina, Jose J. ^{[2
]}

Perez-Sanchez, Alfonso ^{[1
]}

Illescas, Beatriz M. ^{[1
]}

Rojo, Javier ^{[2
]}

Martin, Nazario ^{[1
,3
]}

机构：

[1] Univ Complutense Madrid, Dept Quim Organ, Fac CC Quim, Av Complutense S-N, E-28040 Madrid, Spain

[2] Univ Seville, CSIC, IIQ, Glycosyst Lab, Av Amer Vespucio 49, Seville 41092, Spain

[3] IMDEA Nanosci, Campus Cantoblanco, Madrid 28049, Spain

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 69期

基金：

欧洲研究理事会;

关键词：

CRYSTAL-STRUCTURE; FUNCTIONALIZATION; CYCLOADDITION; FULLERENES; FRAMEWORK;

D O I：

10.1039/c6cc05484f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of a new highly symmetric hexakis adduct of C-60 appended with 12 cyclooctyne moieties has been carried out. This compound has been used for the copper-free strain-promoted cycloaddition reaction to a series of azides with excellent yields. This strategy for the obtention of clicked adducts of [60]fullerene is of special interest for biological applications.

引用

页码：10544 / 10546

页数：3

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