Highly sensitive graphene biosensors based on surface plasmon resonance

被引：770
|
作者：
Wu, L. [1 ]
Chu, H. S. [1 ]
Koh, W. S. [1 ]
Li, E. P. [1 ]
机构：
[1] ASTAR Inst High Performance Comp, Adv Photon & Plasmon Grp, Singapore 138632, Singapore
来源：
OPTICS EXPRESS | 2010年 / 18卷 / 14期
关键词：
DNA;
D O I：
10.1364/OE.18.014395
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
A surface plasmon resonance (SPR) based graphene biosensor is presented. It consists of a graphene sheet coated above a gold thin film, which has been proposed and experimentally fabricated recently [ChemPhysChem 11, 585 (2010)]. The biosensor uses attenuated total reflection (ATR) method to detect the refractive index change near the sensor surface, which is due to the adsorption of biomolecules. Our calculations show that the proposed graphene-on-gold SPR biosensor (with L graphene layers) is (1 + 0.025 L) x gamma (where gamma > 1) times more sensitive than the conventional gold thin film SPR biosensor. The improved sensitivity is due to increased adsorption of biomolecules on graphene (represented by the factor gamma) and the optical property of graphene. (C) 2010 Optical Society of America
引用
收藏
页码：14395 / 14400
页数：6
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