Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism

被引：56

作者：

Pitskel, Naomi B. ^{[1
]}

Bolling, Danielle Z. ^{[1
]}

Hudac, Caitlin M. ^{[1
]}

Lantz, Stephen D. ^{[2
]}

Minshew, Nancy J. ^{[2
]}

Vander Wyk, Brent C. ^{[1
]}

Pelphrey, Kevin A. ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Yale Child Study Ctr, New Haven, CT 06520 USA

[2] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA

来源：

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2011年 / 41卷 / 12期

关键词：

Autism; Direct gaze; Averted gaze; Gaze processing; Functional magnetic resonance imaging; TEMPORO-PARIETAL JUNCTION; EYE-GAZE; FACIAL EXPRESSION; CHILDREN; SPECTRUM; CONTACT; PERCEPTION; REGIONS; MIND; ACTIVATION;

D O I：

10.1007/s10803-011-1197-x

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Prior studies have indicated brain abnormalities underlying social processing in autism, but no fMRI study has specifically addressed the differential processing of direct and averted gaze, a critical social cue. Fifteen adolescents and adults with autism and 14 typically developing comparison participants viewed dynamic virtual-reality videos depicting a simple but realistic social scenario, in which an approaching male figure maintained either direct or averted gaze. Significant group by condition interactions reflecting differential responses to direct versus averted gaze in people with autism relative to typically developing individuals were identified in the right temporoparietal junction, right anterior insula, left lateral occipital cortex, and left dorsolateral prefrontal cortex. Our results provide initial evidence regarding brain mechanisms underlying the processing of gaze direction during simple social encounters, providing new insight into the social deficits in individuals with autism.

引用

页码：1686 / 1693

页数：8

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[1] Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism
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Kevin A. Pelphrey
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