Dendritic cells and transmission of HIV-1

被引:36
|
作者
Sewell, AK [1 ]
Price, DA
机构
[1] John Radcliffe Hosp, Nuffield Dept Med, Oxford OX3 9DU, England
[2] John Radcliffe Hosp, MRC, Human Immunol Unit, Weatherall Inst Mol Med, Oxford OX3 9DS, England
关键词
D O I
10.1016/S1471-4906(01)01866-X
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Sexual transmission of HIV-1 requires that small amounts of virus at mucosal sites of inoculation gain access to replication-permissive cells. Recent observations have increased our understanding of the mechanisms by which this relatively inefficient virus can exploit the migratory nature of dendritic cells to establish infection within the host.
引用
收藏
页码:173 / 175
页数:3
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