Synthesis of Novel Amino Acids Incorporating Zinc-Binding Groups as Inhibitors of HDAC1:MTA1 Co-repressor Complex

被引：0
|
作者：
Mahindra, Amit [1 ]
Watson, Peter [2 ]
Millard, Chris [2 ]
Schwabe, John [2 ]
Jamieson, Andrew [1 ]
机构：
[1] Univ Glasgow, Glasgow, Lanark, Scotland
[2] Univ Leicester, Leicester, Leics, England
来源：
JOURNAL OF PEPTIDE SCIENCE | 2018年 / 24卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
P219
引用
收藏
页码：S158 / S159
页数：2
相关论文
共 11 条
  • [1] Synthesis of HDAC Substrate Peptidomimetic Inhibitors Using Fmoc Amino Acids Incorporating Zinc-Binding Groups
    Mahindra, Amit
    Millard, Christopher J.
    Black, Iona
    Archibald, Lewis J.
    Schwabe, John W. R.
    Jamieson, Andrew G.
    ORGANIC LETTERS, 2019, 21 (09) : 3178 - 3182
  • [2] GSE1 links the HDAC1/CoREST co-repressor complex to DNA damage
    Vcelkova, Terezia
    Reiter, Wolfgang
    Zylka, Martha
    Hollenstein, David M.
    Schuckert, Stefan
    Hartl, Markus
    Seiser, Christian
    NUCLEIC ACIDS RESEARCH, 2023, 51 (21) : 11748 - 11769
  • [3] Reciprocal Effects of HDAC1 and HDAC2 Deletion on Renal Cold Ischemia Survival and Nuclear Co-Repressor Complex Expression.
    Aufhauser, D., Jr.
    Murken, D.
    Wang, Z.
    Samanta, A.
    Ge, G.
    Bhatti, T.
    Hancock, W.
    Levine, M.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2016, 16 : 634 - 634
  • [4] EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin
    Tong, Z-T
    Cai, M-Y
    Wang, X-G
    Kong, L-L
    Mai, S-J
    Liu, Y-H
    Zhang, H-B
    Liao, Y-J
    Zheng, F.
    Zhu, W.
    Liu, T-H
    Bian, X-W
    Guan, X-Y
    Lin, M. C.
    Zeng, M-S
    Zeng, Y-X
    Kung, H-F
    Xie, D.
    ONCOGENE, 2012, 31 (05) : 583 - 594
  • [5] EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin
    Z-T Tong
    M-Y Cai
    X-G Wang
    L-L Kong
    S-J Mai
    Y-H Liu
    H-B Zhang
    Y-J Liao
    F Zheng
    W Zhu
    T-H Liu
    X-W Bian
    X-Y Guan
    M C Lin
    M-S Zeng
    Y-X Zeng
    H-F Kung
    D Xie
    Oncogene, 2012, 31 : 583 - 594
  • [6] Enhancer recruitment of a RUNX1, HDAC1 and TLE3 co-repressor complex by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia
    Simeoni, Fabrizio
    Somervaille, Tim C. P.
    MOLECULAR & CELLULAR ONCOLOGY, 2021, 8 (06)
  • [7] MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail
    Huang, Wenqing
    Chen, Jianxiong
    Liu, Xunhua
    Liu, Xuming
    Duan, Shiyu
    Chen, Lixia
    Liu, Xiaoting
    Lan, Jiawen
    Zou, Ying
    Guo, Dan
    Zhou, Jun
    EXPERIMENTAL CELL RESEARCH, 2021, 406 (01)
  • [8] The co-repressor complex mSin3A/HDAC1 is involved in the down-regulation of CRTC2 target genes during B cell differentiation.
    Arancibia, Y. V.
    Zambrano, A. H.
    Carcamo, C.
    MOLECULAR BIOLOGY OF THE CELL, 2017, 28
  • [9] SREBP1, targeted by miR-18a-5p, modulates epithelial-mesenchymal transition in breast cancer via forming a co-repressor complex with Snail and HDAC1/2
    Zhang, Ning
    Zhang, Hanwen
    Liu, Ying
    Su, Peng
    Zhang, Jiashu
    Wang, Xiaolong
    Sun, Mingjuan
    Chen, Bing
    Zhao, Wenjing
    Wang, Lijuan
    Wang, Huiyun
    Moran, Meena S.
    Haffty, Bruce G.
    Yang, Qifeng
    CELL DEATH AND DIFFERENTIATION, 2019, 26 (05): : 843 - 859
  • [10] SREBP1, targeted by miR-18a-5p, modulates epithelial-mesenchymal transition in breast cancer via forming a co-repressor complex with Snail and HDAC1/2
    Ning Zhang
    Hanwen Zhang
    Ying Liu
    Peng Su
    Jiashu Zhang
    Xiaolong Wang
    Mingjuan Sun
    Bing Chen
    Wenjing Zhao
    Lijuan Wang
    Huiyun Wang
    Meena S. Moran
    Bruce G. Haffty
    Qifeng Yang
    Cell Death & Differentiation, 2019, 26 : 843 - 859
12